Research finds ‘heartbreak’ syndrome linked to cancer and brain response to stress

“Heartbreak” syndrome, heart Temporary weakening is associated with the brain’s response to stress, a 2019 study found

In an article published on European Heart Journal In March, Swiss researchers said they found an association between the way the brain communicates with the heart and the broken heart syndrome, also called Takotsubo syndrome (TTS).

Due to intense emotional events, TTS is a rare temporary condition It Weakens the left ventricle Interrupt normal pump function.

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For them the studySwiss neuroscientists and cardiologists performed MRI brain scans on 15 TTS patients (on average, about 1 year after diagnosis) and compared them to scans from 39 healthy individuals.

Specifically, we focused on four brain areas that control emotion, motivation, learning, and memory, and share information with each other. The two areas they analyzed, the amygdala and the cingulate, help control the autonomic nervous system and cardiac function.

In analyzing the scan, researchers were able to correlate the function of these “areas” with TTS.

“We found that TTS patients had reduced communication between brain areas related to emotion processing and the autonomic nervous system that controls the unconscious functioning of the body, compared to healthy people.” Pudding Zurich Said in a statement.

“For the first time, we have identified a correlation between changes in the functional activity of specific brain regions and TTS. This strongly supports the idea that the brain is involved in the mechanisms underlying TTS. And physical stress are strongly associated with TTS, and it has been hypothesized that overstimulation of the autonomic nervous system may trigger TTS events, “added Templin.

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However, researchers did not perform MRI scans of the brains of TTS patients at the onset of symptoms, so they could not determine whether reduced communication between the brain and heart was the cause of TTS or vice versa .

“Our results suggest that additional research needs to be performed to determine if this is a causal link,” said a senior researcher at the University of Zurich Hospital and co-author of the study. Said Dr. Jelena Ghadri.

“I hope this study provides a new starting point for studying TTS, which goes far beyond the ‘broken heart’ syndrome, and where the brain-heart interaction is clearly and completely understood. I understand that I don’t. “

The symptoms of TTS (chest pain and shortness of breath) are similar to those of a heart attack.

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“If you look at the disease, takotsubo cardiomyopathy, or the heartbreak syndrome, there is an outrageous amount of stress, all the stress hormones you feel in your head are released into your body, and your heart is almost in a state of shock. The moment you do it looks like a heart attack. “Cardiologist Suzanne Steinbaum said, I told Fox News before.

Many recover quickly from TTS, but in rare cases can be fatal. Steinbaum recommends that any person who experiences symptoms such as shortness of breath, chest pain, or motion pal see a doctor immediately.

TTS is more closely related to sad events, such as the death or unemployment of a loved one, but also very happy events, such as a wedding or winning a lot of money.

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In addition, international studies from July have linked TTS to cancer.

In a study published by American Heart Association JournalResearchers have found that one in six people with TTS has some form of cancer, stating that “it is unlikely to live for five years after the outbreak.”

“Of the 1,604 patients with heartbreak syndrome at the International Takotsubo Registry, 267 patients or 1 in 6 (average age 69.5 years, 87.6% women) had cancer,” the study notes. “The most frequent type of malignancy is breast cancer, followed by tumors that affect the gastrointestinal system, respiratory tract, internal organs, skin and other areas.”

“ Screening for cancer to improve overall survival may benefit patients with heartbreak syndrome, ” said Templin, who participated in a previous study published in the European Heart Journal. Was.

“Our study shows that syncope syndrome needs to be considered in patients undergoing the diagnosis or treatment of cancer experiencing chest pain, shortness of breath, or abnormal ECGs, among oncologists and hematologists. You need to recognize it. “

Fox News’s Lindsay Carlton contributed to this report.

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